Hello, my name is David Moore, and I have Asperger’s. Asperger’s is a high‐functioning form of autism. I am now fifty-one years old, and I would like to share with you my most recent understanding of autism and the endocannabinoid system.
As the picture above illustrates, I have almost always felt trapped inside my mind. And to compound this claustrophobic view of life, I almost always seemed to offend the people I spoke to; and this only served to drive me further inside myself while further supporting my agoraphobic tendencies.
Eventually, and to spark the necessary creative‐tension in my life, I began to ‘trek‐the‐path’ known as ‘going‐without’. The crucible of this ‘outward‐bound’ exercise was my desire to belong. For my autism made me wander the forest alone, and forever frustrated.
And the smithy’s hammer to my ‘forge of misunderstanding’, were the cultural indoctrinations that always seem to escape my grasp. And those indoctrinations were all socially transmitted ‘dis‐eases’ from my limited and autisticly warped perspective. For while we are all social animals, I am inept.
You see, it is important to understand the psychological paradigm of an autistic child, before considering the biochemical affects of an autistic brain, for we are not ‘neuro‐typical’ by any means. So please understand that my ‘forge of misunderstanding’ was caused by my autistic brain wiring.
And this abnormality became extremely detrimental to my health, because of the malfunctioning endocannabinoid system that further disabled my regenerative abilities. For not only did I NOT sleep for forty years, I also in the early stages of diabetes and heart disease, while contracting cancer, and an autoimmune disorder known as celiac disease. And only after going into renal failure, did I begin working on a functional foods approach...
To be autistic is to have a brain that is wired differently from the typical brain. And in most cases, the hippocampus and the amygdala are not ‘hooked‐up’ as well as the neurotypical brain. And these two regions of the brain are involved in processing emotion, and have a great influence on the ability to learn and retain memories.
And my experience with this warped reality, as a high functioning autistic freak, was extraordinary in nature. And while I always suffered from a life of extreme anxiety, an insufficient diet of processed foods, an overdose of gmo corn syrup, and an overindulgence of bread; only after leaving home did I begin to comprehend the secluded and intimate nature of my small‐town upbringing (an how truly agoraphobic I was).
Meaning, where I grew up as a child, I could easily find solitude, and with vast open areas of water. But away at college, sharing a room with a stranger, and going to huge classes... Well, I didn’t have a chance at processing all of the adjustments required to survive. But I eventually scaled down my schools, and finally found a graduate college that was a godsend to me.
But every time I entered the corporate world of greed, lies, and thievery... I ended up spiraling out of control while being sexually harassed by those around me. And these compounded stressors eventually caused me to contract post‐traumatic stress disorder (PTSD), which led to a microbiome deficiency, as well as having a degrading effect on my overall immune system. And as you can see from the infographic above, my autism already causes me to live in a perilous biochemical situation.
I remember this one time I was given a cough and flu medicine during my teenage years. It had some antipsychotic in it called Benadryl. Well, I ended up sleeping for two whole days. I had never slept that good in my life. That is, until I discovered opioids. But that’s a whole‐nother‐story.
So as my journey buries me deeper in the ground, I search for substances to ease my suffering. And these escapades eventually lead to a greater manic‐depression, exacerbated by an autoimmune disorder known as celiac disease. A disease that is mostly triggered by the prolonged ingestion of genetically modified wheat (lots of glyphosate), in combination with a weakened immune system.
And the Manic Depression, synergized with various and extreme environmental factors, led to PTSD; which led to more substance abuse, which led to a more weakened immune system, which led to pre-diabetes, then to celiac disease. And the celiac disease ended up destroying my gut flora, while the gluten from gmo‐wheat was wreaking havoc on my prefontal cortex (the decision making part of our brains). All of this eventually led to cancer.
And only when renal failure hit, as a result of acute kidney damage, did I begin to realize that my death was imminent. And while my death‐wish was being fulfilled, I decided to take drastic measures to reverse my condition. I went on a gluten‐free, olive‐oil‐free, raw‐organic, ovo-vegan‐diet (lots of pasture raised organic eggs).
And I began consuming cannabis‐coconut‐oil. By infusing cannabis into coconut‐oil, you facilitate the entry into the liver so it can be processed rapidly. And coconut‐oil is preferred because of its high amount of essential fatty acids, thus making it a good binding agent for the cannabinoids.
And half the fat in coconut‐oil is comprised of a fat that is not frequently found in nature, lauric‐acid. Lauric‐acid has been called a ‘miracle’ ingredient due to its health promoting capabilities and is also present in a mother’s milk. In fact, it can be found in two main dietary sources: small amounts in butterfat, and larger amounts in coconut oil.
In the body lauric‐acid is converted to monolaurin, which is reported to be a potent substance... with the cannabinoids helping to up-regulate the immune dysregulation that occurs as a result of the autistic brain, as well as improving glycemic control, while dramatically reducing inflammation.
A recent study from the Biomedical Center for Autism Research and Treatment suggests the CB2 receptor as a potential therapeutic target for the cannabis infused coconut‐oil. This study was the first to demonstrate the up‐regulation of CB2 receptors in autistic endocannabinoid systems.
The CB2 receptor enhancements demonstrate that the endocannabinoid system is involved in the maintenance of autism. According to the findings, the endocannabinoid system may represent a novel treatment opportunity for cannabis therapy with autistic minds.
And that’s because the up‐regulation of the CB2 receptors enhances the peripheral organs ability to manage the immune system. And endocannabinoid signaling, in general, affects memory formation, learning, pain, and other important regenerative processes.
Since the available pharmacological treatments have limited effectiveness, as well as harmful side‐effects; it is time to use the cannabis solution.
The endocannabinoid system is an intricate network of endocannabinoids, their receptors, and the associated enzymes; and all play critical roles in maintaining the body’s homeostasis.
The endocannabinoid systesm (ECS) has been implicated in a broad spectrum of conditions ranging from appetite regulation to cancer. Recently, evidence is emerging that demonstrates the involvement of the ECS in modulating several developmental disorders (such as epilepsy).
And the cannabis that calms seizures has low levels of THC and high levels of CBD’s (cannabinoids). CBD’s display no psychoactivity (users don’t ‘get high’). CBD’s have been shown to exhibit several biological actions including: anticonvulsive, sedative, hypnotic, antipsychotic, anti‐inflammatory and neuroprotective properties.
And it is important to note, that in most cases, scientists make decisions based on evidence gained from an experiment with extensive controls. But the differences in CBD composition vary from from batch to batch, thus making cannabis experiments too organic for current scientific rigidity.
Patients and Caregivers must learn to take advantage of the vast number of cannabis strains that are available, and determine which is the most effective for their purposes. The goal is to first determine which strain works for a particular patient, then characterize that strain in terms of composition and pharmacology, then manufacture the strains that are most effective for the patients at large.
The research is in its infancy regarding the impact of cannabis use as a potential therapy. And further research is required in order to better understand the connection between the endocannabinoid system and autism spectrum disorders.
The biochemical affects, and the endocannabinoid system, are core considerations when helping ourselves to self-heal. Then we must overlay the paradigm of the person we are attempting to help. And this entails historical diet, family environments, stressors, economic situation, emotional and sexual abuse, cultural indoctrinations, and on and on; for the epigenome is influenced by the environment, and the epigenome triggers our genetic predispositions to certain diseases.
So please understand that our emotional health, the biochemical effects of our diet, and the endocannabinoid system are huge influences on our epigenome. And what we eat has a great influence on our susceptibility to disease, as well as on our progeny’s predisposition to disease.
oh tiger‐like child king
Look at me!
I am free!
For I see.
And that cannot be?
How is it that I came by this wonder?
For has it not always been thunder?
And the lightning bolts that scorched my earth?
have always been, since my birth?
Do not fray at the site of my scars.
For they are now the stripes that earned me mars.
Grieve not for my loss.
For only I can heal the cross.
On which I have borne witness...
And from which I have gained sickness.
So as to become an eternal kindness.
As the lamb of blindness...
With the forsaken forever marring my way.
David Harold Moore, CEO
I have alway striven for the golden mean...